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. 2001 Oct;3(5):253-8.

Clinical correlates of psychiatric comorbidity in bipolar I patients

E Vieta  1 , F Colom, B Corbella, A Martínez-Arán, M Reinares, A Benabarre, C Gastó
Affiliations
  • PMID: 11903208

Clinical correlates of psychiatric comorbidity in bipolar I patients

E Vieta et al. Bipolar Disord. 2001 Oct.

Abstract

Objectives: To ascertain the clinical implications of psychiatric comorbidity in the course and outcome of bipolar I patients.

Methods: One hundred and twenty-nine bipolar I outpatients in remission [Young Mania Rating Scale (Y-MRS) < 7, Hamilton Depression Rating Scale (HDRS) < 9] were assessed by means of the Structured Clinical Interview for DSM-III-R axis I and axis II (SCID-I and SCID-II) in order to detect all possible psychiatric comorbid diagnoses. The sample was split according to the presence of psychiatric comorbidity and the groups were compared.

Results: Psychiatric comorbidity was detected in 31% of the sample. A higher number of mixed features, depressive episodes and suicide attempts and a predominance of depressive onset amongst comorbid bipolar patients were the most relevant differences between the two groups.

Conclusions: There is an association between depression, suicidality and comorbidity in bipolar I disorder. As comorbidity had a clear relevance in the course and outcome of bipolar illness, this issue should be specifically assessed in clinical practice.

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