An analysis of the time course of gustatory neural adaptation in the rat

Abstract

Neural responses were recorded from the rat chorda tympani nerve following stimulation of the tongue with several concentrations of NaCl. These responses were integrated using a fast time constant (47 ms), and the time course of the decline in neural discharge from the peak of the transient response was computer analyzed. The time course of the adaptation process was described by a constant term and two exponentially decaying components, which most likely reflect the existence of two separate mechanisms contributing to the adaptation process in taste. The constant term and the amplitude of the second gradual exponential decay were correlated with NaCl concentration, whereas the amplitude of the initial rapidly declining exponential component was independent of stimulus intensity. The initial transient response of the chorda tympani nerve may be a function of the rate of stimulus adsorption, whereas the gradual second decline in the neural response may reflect an adaptive mechanism of the taste receptor cell.