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Comment
. 2002 Mar 19;99(6):3359-61.
doi: 10.1073/pnas.072084199.

Spliceosomal introns in a deep-branching eukaryote: the splice of life

Patricia J Johnson  1
Affiliations
Comment

Spliceosomal introns in a deep-branching eukaryote: the splice of life

Patricia J Johnson. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Representative tree depicting the three domains of life, Bacteria, Archaea, and Eukaryotes, with emphasis on the eukaryotic branch. The tree is based on small subunit rRNA sequences originally published by Sogin (32) and was redrawn by Dacks and Doolittle (2). This tree has provided enormous intellectual stimuli upon which numerous theories have been built and tested. Construction of eukaryotic phylogenies is a continuous process being steadily fed and modified by the availability of new data in this era of genomics. As discussed by Nixon et al. (11) in this issue of PNAS, the precise nature of deep-branching, divergent lineages and their relationship to other eukaryotes continues to be challenged and debated. [Reproduced with permission from ref. (Copyright 2001, Elsevier Science).]
Figure 2
Figure 2
Giardia lamblia is a facultative anaerobic and obligate parasite. Nixon et al. report the presence of a spliceosomal intron in the genome of Giardia. Before this report, spliceosomal introns had been observed in metazoa, yeast, and, moderately, deep-branching protists (2, 12), but not in the deepest branches of the rRNA-based eukaryotic tree. [Reproduced with permission from the Atlas of Medical Parasitology (AMP), www.cdfound.to.it (Carlo Denegri Foundation).]
See this image and copyright information in PMC

Comment on

  • A spliceosomal intron in Giardia lamblia.
    Nixon JE, Wang A, Morrison HG, McArthur AG, Sogin ML, Loftus BJ, Samuelson J. Nixon JE, et al. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3701-5. doi: 10.1073/pnas.042700299. Epub 2002 Feb 19. Proc Natl Acad Sci U S A. 2002. PMID: 11854456 Free PMC article.

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