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Review
. 2002 Jan;2(1):28-36.
doi: 10.1038/nri700.

Modelling viral and immune system dynamics

Alan S Perelson  1
Affiliations
Review

Modelling viral and immune system dynamics

Alan S Perelson. Nat Rev Immunol. 2002 Jan.

Abstract

During the past 6 years, there have been substantial advances in our understanding of human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C virus, that cause chronic infection. The use of mathematical modelling to interpret experimental results has made a significant contribution to this field. Mathematical modelling is also improving our understanding of T-cell dynamics and the quantitative events that underlie the immune response to pathogens.

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