[Ultrastructure of nuclear bodies in connective tissue cells of psoriatic lesions (author's transl)]

Abstract

Electron microscopic observations were made in 6 psoriatic lesions of the skin. All specimens showed an increased number of nuclear bodies containing glycogen and lipids in the nuclear plasma of connective tissue cells. The results indicate an activation of connective tissue cell metabolism. They are discussed in connection with previously described signs of the participation of mesenchymal tissue in the psoriatic skin reaction. The increased metabolism could be part of a "nonspecific mesenchymal tissue reaction".