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Review
. 2002 Mar 23;324(7339):714-8.
doi: 10.1136/bmj.324.7339.714.

Cancer chemoprevention

Peter Greenwald  1
Affiliations
Review

Cancer chemoprevention

Peter Greenwald. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Multistage carcinogenesis: processes and prevention strategies. The initiation stage is characterised by the conversion of a normal cell to an initiated cell in response to DNA damaging agents (genetic damage indicated by an X). The promotion stage is characterised by the transformation of an initiated cell into a population of preneoplastic cells, a result of alterations in gene expression and cell proliferation. The progression stage involves the transformation of the preneoplastic cells to a neoplastic cell population as a result of additional genetic alterations. (Adapted from Hursting et al (1999) with authors' permission)
Figure 2
Figure 2
Garlic (Allium sativum) contains chemicals that suppress cell division in human colon tumour cells by interfering with the cell cycle
See this image and copyright information in PMC

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    1. Hursting SD, Slaga TJ, Fischer SM, DiGiovanni J, Phang JM. Mechanism-based cancer prevention approaches: targets, examples, and the use of transgenic mice. J Natl Cancer Inst. 1999;91:215–225. - PubMed
    1. Chemoprevention Working Group. Prevention of cancer in the next millennium: report of the Chemoprevention Working Group to the American Association for Cancer Research. Cancer Res. 1999;59:4743–4758. - PubMed

MeSH terms