Reduced transient outward K+ current and cardiac hypertrophy: causal relationship or epiphenomenon?
- PMID: 11909810
- DOI: 10.1161/01.res.0000014284.39141.8c
Reduced transient outward K+ current and cardiac hypertrophy: causal relationship or epiphenomenon?
Comment on
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Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit.Circ Res. 1998 Sep 7;83(5):560-7. doi: 10.1161/01.res.83.5.560. Circ Res. 1998. PMID: 9734479
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Targeted expression of a dominant-negative K(v)4.2 K(+) channel subunit in the mouse heart.Circ Res. 1999 Nov 26;85(11):1067-76. doi: 10.1161/01.res.85.11.1067. Circ Res. 1999. PMID: 10571538
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Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes.Circ Res. 2002 Mar 22;90(5):578-85. doi: 10.1161/01.res.0000012223.86441.a1. Circ Res. 2002. PMID: 11909822
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