Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2001 Oct;79(10):526-9.

[Diagnosis of holoprosencephalia. Report of 17 cases]

[Article in French]
S Siala Gaigi  1 , A Masmoudi, M B Chennoufi, S Jabnoun, B Ben Romdhane, M Chaabouni, A Mabrouk, K Neji, A Chabchoub, E Sfar, I Lebbi, F Zouari, H Chelli, H Rezigua, H Chaabouni, N Khrouf
Affiliations
  • PMID: 11910693
Case Reports

[Diagnosis of holoprosencephalia. Report of 17 cases]

[Article in French]
S Siala Gaigi et al. Tunis Med. 2001 Oct.

Abstract

Objective: To establish the epidemiologic profile of holoprosencephalia and determine benefits of ultrasound and foetopathologic examination to the diagnostic. METHODS AN MATERIAL: [corrected] Retrospective study about 17 cases of holoprosencephalia observed in CMNT between Janaury 1992 and September 2000.

Results: Ultrasound diagnosis was made in 13 cases (75%). Ultrasound criteria were; absence of median structure of the brain and unique ventricule. The prognosis was always bad. Foetopathologic examination revealed 7 cases of lobar holoproencephalia and 10 of semi lobar. Fascial dysmorphia were noted in 82% of cases.

Conclusion: The foetopathology and genetic counselling looking for fascial, dysmorphia in family's members gives a good evaluation of recurrences.

PubMed Disclaimer

Publication types

LinkOut - more resources