Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2002 Mar 25;162(6):713-5.
doi: 10.1001/archinte.162.6.713.

Aseptic meningitis associated with rofecoxib

Renan A Bonnel  1 , Maria L Villalba, Claudia B Karwoski, Julie Beitz
Affiliations
Case Reports

Aseptic meningitis associated with rofecoxib

Renan A Bonnel et al. Arch Intern Med. .

Abstract

Rofecoxib is a nonsteroidal anti-inflammatory drug that is reported to act by selectively inhibiting cyclooxygenase-2. A review and analysis of reports sent to the Spontaneous Reporting System of the Food and Drug Administration, Rockville, Md, suggest that aseptic meningitis is associated with rofecoxib use. To our knowledge, there have been no published reports of aseptic meningitis occurring in association with rofecoxib use to date. We report 5 serious cases of aseptic meningitis associated with rofecoxib use.

PubMed Disclaimer

Publication types

MeSH terms