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. 2002 Jan;55(1):25-9.
doi: 10.7164/antibiotics.55.25.

CJ-21,058, a new SecA inhibitor isolated from a fungus

Yutaka Sugie  1 , Sae Inagaki, Yoshinao Kato, Hiroyuki Nishida, Chang-Hong Pang, Toshiyuki Saito, Shinichi Sakemi, Fadia Dib-Hajj, John P Mueller, Joyce Sutcliffe, Yasuhiro Kojima
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Free article

CJ-21,058, a new SecA inhibitor isolated from a fungus

Yutaka Sugie et al. J Antibiot (Tokyo). 2002 Jan.
Free article

Abstract

A new equisetin derivative, CJ-21,058 (I) was isolated from the fermentation broth of an unidentified fungus CL47745. It shows antibacterial activity against Gram-positive multi-drug resistant bacteria by inhibiting ATP-dependent translocation of precursor proteins across a bacterial cell membrane.

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