Microbiologic evaluation of commercial probiotics

Abstract

Objective: To evaluate contents of commercial probiotic products marketed for veterinary or human administration.

Design: Microbiologic culture assay.

Sample population: 8 veterinary probiotics and 5 human probiotics.

Procedure: Quantitative bacteriologic culture was performed on all products, and isolates were identified via biochemical characteristics. Comparison of actual contents versus label claims was performed.

Results: Label descriptions of organisms and concentrations accurately described the actual contents of only 2 of 13 products. Five veterinary products did not specifically list their contents. Most products contained low concentrations of viable organisms. Five products did not contain 1 or more of the stated organisms, and 3 products contained additional species. Some products contained organisms with no reported probiotic effects; some of these organisms could be pathogens.

Conclusions and clinical relevance: Most commercial veterinary probiotic preparations are not accurately represented by label claims. Quality control appears to be poor for commercial veterinary probiotics.