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Comment
. 2002 Apr 2;99(7):4135-7.
doi: 10.1073/pnas.082107399.

Imaging the progression of Alzheimer pathology through the brain

A David Smith  1
Affiliations
Comment

Imaging the progression of Alzheimer pathology through the brain

A David Smith. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Photograph of the median aspect of the human brain (front to left) showing two parts of the MTL, the hippocampus, and parahippocampal gyrus. The third part is the amygdala.
Figure 2
Figure 2
Diagrammatic representation of the neural projections from the medial temporal lobe (red) to the neocortex (Top, lateral aspect; Middle, medial aspect; Bottom, ventral aspect). Areas shown in blue are those where reduced metabolism or reduced blood flow are found in AD on functional imaging. Several of these areas showed atrophy in the study by Scahill et al. (6).
Figure 3
Figure 3
Postulated sequence of spread of neurofibrillary pathology in AD, showing the medial aspect of the cerebral cortex. The depth of the red color is in proportion to the density of tangles (based on refs. and 28). Several of the red areas showed atrophy in the study by Scahill et al. (6).
See this image and copyright information in PMC

Comment on

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