Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2002 Mar;9(3):459-70.
doi: 10.1016/s1097-2765(02)00482-3.

Mechanisms of caspase activation and inhibition during apoptosis

Yigong Shi  1
Affiliations
Free article
Review

Mechanisms of caspase activation and inhibition during apoptosis

Yigong Shi. Mol Cell. 2002 Mar.
Free article

Abstract

Caspases are central components of the machinery responsible for apoptosis. Recent structural and biochemical studies on procaspases, IAPs, Smac/DIABLO, and apoptosome have revealed a conserved mechanism of caspase activation and inhibition. This article reviews these latest advances and presents our current understanding of caspase regulation during apoptosis.

PubMed Disclaimer

Publication types

LinkOut - more resources