Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1975 Nov;16(11):913-7.
doi: 10.1136/gut.16.11.913.

Jaundice due to carbimazole

M Lunzer, S N Huang, J Ginsburg, M Ahmed, S Sherlock
Case Reports

Jaundice due to carbimazole

M Lunzer et al. Gut. 1975 Nov.

Abstract

On three occasions, a 63 year old housewife with hyperthyroidism developed a reaction which included fever, pruritus, malaise, and, on one occasion, jaundice one to 17 days after taking carbimazole. Challenge with carbimazole was followed within 12 hours by abdominal pain, pruritus, and increased serum transaminase levels. Light microscopy of a liver biopsy showed increase of portal zone cellularity over the control and the electron microscopy revealed fine structural changes compatible with drug-related liver injury.

PubMed Disclaimer

References

    1. JAMA. 1973 Feb 26;223(9):1028-9 - PubMed
    1. Am J Med. 1971 Mar;50(3):317-24 - PubMed
    1. Ann Intern Med. 1969 Sep;71(3):467-77 - PubMed
    1. Gastroenterology. 1962 Jul;43:84-7 - PubMed
    1. JAMA. 1968 Nov 18;206(8):1787-9 - PubMed

Publication types

LinkOut - more resources