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Review
. 2002 Apr 2;12(7):R245-7.
doi: 10.1016/s0960-9822(02)00782-0.

Chromatin remodeling: nucleosomes bulging at the seams

Craig L Peterson  1
Affiliations
Free article
Review

Chromatin remodeling: nucleosomes bulging at the seams

Craig L Peterson. Curr Biol. .
Free article

Abstract

ATP-dependent chromatin remodeling enzymes, such as SWI/SNF, hydrolyze thousands of ATPs to regulate gene expression on chromatin fibers. Recent mechanistic studies suggest that these enzymes generate localized changes in DNA topology that drive formation of multiple, remodeled nucleosomal states.

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