Cell signaling: life or death decisions of ras proteins
- PMID: 11937045
- DOI: 10.1016/s0960-9822(02)00787-x
Cell signaling: life or death decisions of ras proteins
Abstract
The discovery of a new downstream target for the Ras GTPases - a Nore1-Mst1 protein complex - reveals a mechanism by which Ras can promote apoptosis, and suggests that the influence of Ras on cell survival or death depends upon the relative level of activation of its various target proteins.
Comment on
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Identification of a novel Ras-regulated proapoptotic pathway.Curr Biol. 2002 Feb 19;12(4):253-65. doi: 10.1016/s0960-9822(02)00683-8. Curr Biol. 2002. PMID: 11864565
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