Intercellular adhesion, signalling and the cytoskeleton
- PMID: 11944044
- DOI: 10.1038/ncb0402-e101
Intercellular adhesion, signalling and the cytoskeleton
Abstract
Connections between the cytoskeleton and intercellular junctions profoundly influence cell shape and motility. It is becoming increasingly clear that in addition to structural functions, components of the adhesion apparatus also possess signalling capabilities. Recent studies suggest that their dual function may provide the means to integrate changes in morphology and gene expression during tissue and organ development.
Similar articles
-
Cell-cell junctions in focus - imaging junctional architectures and dynamics at high resolution.J Cell Sci. 2024 Oct 15;137(20):jcs262041. doi: 10.1242/jcs.262041. Epub 2024 Oct 31. J Cell Sci. 2024. PMID: 39480660 Review.
-
Desmosomes: adhesive strength and signalling in health and disease.Biochem J. 2010 Aug 1;429(3):419-33. doi: 10.1042/BJ20100567. Biochem J. 2010. PMID: 20626351 Review.
-
Intercellular adhering junctions with an asymmetric molecular composition: desmosomes connecting Merkel cells and keratinocytes.Cell Tissue Res. 2011 Oct;346(1):65-77. doi: 10.1007/s00441-011-1260-0. Epub 2011 Oct 19. Cell Tissue Res. 2011. PMID: 22006253 Clinical Trial.
-
Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest.Exp Cell Res. 2001 Nov 1;270(2):199-213. doi: 10.1006/excr.2001.5348. Exp Cell Res. 2001. PMID: 11640884
-
1,25-dihydroxyvitamin D3 stimulates the assembly of adherens junctions in keratinocytes: involvement of protein kinase C.Endocrinology. 1997 Jun;138(6):2241-8. doi: 10.1210/endo.138.6.5156. Endocrinology. 1997. PMID: 9165007
Cited by
-
Collective and single cell behavior in epithelial contact inhibition.Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):739-44. doi: 10.1073/pnas.1007809109. Epub 2012 Jan 6. Proc Natl Acad Sci U S A. 2012. PMID: 22228306 Free PMC article.
-
Cleavage of E-Cadherin Contributes to Defective Barrier Function in Neosquamous Epithelium.Dig Dis Sci. 2016 Nov;61(11):3169-3175. doi: 10.1007/s10620-016-4315-y. Epub 2016 Sep 22. Dig Dis Sci. 2016. PMID: 27659669 Free PMC article.
-
The Integrated Role of Wnt/β-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics.PLoS Comput Biol. 2016 Jul 18;12(7):e1005007. doi: 10.1371/journal.pcbi.1005007. eCollection 2016 Jul. PLoS Comput Biol. 2016. PMID: 27427963 Free PMC article.
-
The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye.Development. 2009 Oct;136(19):3323-33. doi: 10.1242/dev.038422. Development. 2009. PMID: 19736327 Free PMC article.
-
Epithelial bridges maintain tissue integrity during collective cell migration.Nat Mater. 2014 Jan;13(1):87-96. doi: 10.1038/nmat3814. Epub 2013 Dec 1. Nat Mater. 2014. PMID: 24292420
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases