The influence of Na+ ions on histamine secretion from mast cells induced by NGF or compound 48/80
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- PMID: 11944079
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The influence of Na+ ions on histamine secretion from mast cells induced by NGF or compound 48/80
Cell Mol Biol Lett.
2002.
Abstract
It has been demonstrated that the release of histamine from mast cells by cytokines is strongly dependent on extracellular Ca2+ and Na+ ions. The results of our current research indicate that the removal of extracellular Na+ enhances NGF induced histamine release, but reduces induction by compound 48/80, suggesting that different mechanisms are involved in the secretory process induced by these agents.
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