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. 2002 Apr 18;4(8):1307-10.
doi: 10.1021/ol025604h.

Total synthesis of hectochlorin

Jeannie R P Cetusic  1 , Frederick R Green 3rd, Paul R Graupner, M Paige Oliver
Affiliations

Total synthesis of hectochlorin

Jeannie R P Cetusic et al. Org Lett. .

Abstract

Hectochlorin (1) is a marine natural product with significant fungicidal activity. A synthesis effort was initiated to develop a flexible route to hectochlorin which would allow access to analogues with potentially improved activity and/or attributes relative to the natural product. A successful total synthesis of hectochlorin is described. [structure: see text]

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