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Review
. 2002 Apr;2(2):165-70.
doi: 10.1016/s1471-4892(02)00134-0.

Adenosine A1 receptor antagonists in the kidney: effects in fluid-retaining disorders

William J Welch  1
Affiliations
Review

Adenosine A1 receptor antagonists in the kidney: effects in fluid-retaining disorders

William J Welch. Curr Opin Pharmacol. 2002 Apr.

Abstract

Adenosine A(1) receptor antagonists have been used effectively as potassium-sparing and renal-function-protective diuretics in new studies. In addition, the role of adenosine--acting through adenosine A(1) receptors--in renal autoregulation has been clarified. Finally, the application of adenosine receptor antagonists has been implicated in protection from acute renal failure associated with radiocontrast media treatment.

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