Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2002 Mar;140(3):367-9.
doi: 10.1067/mpd.2002.122468.

Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses

Francis Kasolo  1 , Kennedy Lishimpi, Chifumbe Chintu, Peter Mwaba, Victor Mudenda, Daniel Maswahu, Hiroshi Terunuma, Helen Fletcher, Andrew Nunn, Sebastian Lucas, Alimuddin Zumla
Affiliations

Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses

Francis Kasolo et al. J Pediatr. 2002 Mar.

Abstract

Polymerase chain reaction for Pneumocystis carinii DNA was performed on necropsy lung samples from children by means of P carinii -specific primers.P carinii DNA was identified in 22 of 22 (100%) samples with histologically proven P carinii pneumonia and 13 of 75 (17%) with non-P carinii pneumonia respiratory illness (sensitivity, 100%; specificity, 83%). The low specificity precludes the use of polymerase chain reaction as an alternative to histopathologic diagnosis.

PubMed Disclaimer

Comment in

Publication types

LinkOut - more resources