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Review
. 2002 Apr 5;109(1):5-8.
doi: 10.1016/s0092-8674(02)00711-0.

Antigenic variation and allelic exclusion

Piet Borst  1
Affiliations
Free article
Review

Antigenic variation and allelic exclusion

Piet Borst. Cell. .
Free article

Abstract

Cells often express only one gene from a set of two or more. African trypanosomes appear to accomplish this monoallelic expression by segregating the selected gene into a specific nuclear body. The possibility that such a structure might explain monoallelic expression in other multigene systems is discussed here.

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