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Review
. 2002 May;61(5):463-7.
doi: 10.1136/ard.61.5.463.

Obstruction of the pulmonary artery by granulomatous vasculitis: a clinical, morphological, and immunological analysis

G Schett  1 , S Winkler, U Hollenstein, G Amann, M Willheim, M Prokop, W Klepetko, A Becherer, J Smolen, W Graninger
Affiliations
Review

Obstruction of the pulmonary artery by granulomatous vasculitis: a clinical, morphological, and immunological analysis

G Schett et al. Ann Rheum Dis. 2002 May.
No abstract available

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Figures

Figure 1
Figure 1
Imaging: CT scan, conventional and MR angiography CT scans were performed before starting the immunosuppressive treatment (A) and after two months of treatment (B). An axial thoracic section shows a diffusely infiltrating mass surrounding the aorta and the pulmonary artery. After successful treatment a marked reduction of pathological tissue is evident. Angiography of the pulmonary arteries shows blockage at the origin of the right main pulmonary artery, indicating a complete occlusion of this vessel (C). This is also evident in a three dimensional reconstruction of the heart and the large vessel (D). As a consequence an asymmetrical perfusion of the lungs with hypoperfusion right and compensatory hyperperfusion at the left side is seen (E). MR angiography (F) showed a normal cerebral perfusion; however, a unilateral thickening of the wall of the right internal carotid artery was detected.
Figure 2
Figure 2
Histology. Microphotographs show haematoxylin and eosin stain (A, B) and immunostain (C, D) of biopsy material. Both the centre (C, left) and the wall (W, right) of an intimal granuloma are shown. (A) Giant cells; (B) giant cell engulfing an elastic fibre (arrow); (C) CD4+; and (D) CD8+ T cell in the wall of the granuloma.
See this image and copyright information in PMC

MeSH terms