[Too many unnecessary appendectomies. Leukocyte count and CRP value for safer diagnosis]

Abstract

The increase in leucocyte count is a very early marker of appendiceal inflammation, whereas CRP increases are usually seen only after protracted inflammation such as appendiceal perforation or abscess formation. Acute appendicitis is unlikely in adult patients with normal leucocyte count and CRP value, even if clinical symptoms and signs indicate acute appendicitis. However, a normal leucocyte count and CRP value do not effectively exclude appendicitis in children.