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. 2002 May;10(5):203-5.
doi: 10.1016/s0966-842x(02)02350-8.

Tsg101: HIV-1's ticket to ride

Carol A Carter  1
Affiliations

Tsg101: HIV-1's ticket to ride

Carol A Carter. Trends Microbiol. 2002 May.

Abstract

Recent studies implicate the vacuolar protein-sorting pathway in the transport of the retroviral structural precursor (Gag) protein to its budding site on the plasma membrane of infected cells. This exploitation of the cellular endocytic trafficking machinery to release viral particles could lead to the identification of virus-specific modulators and provide opportunities to design new targeted anti-viral agents.

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