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. 2002 May 2;4(9):1603-5.
doi: 10.1021/ol025805l.

Bifunctional asymmetric catalysis: a tandem nucleophile/Lewis acid promoted synthesis of beta-lactams

Stefan France  1 , Harald Wack, Ahmed M Hafez, Andrew E Taggi, Daniel R Witsil, Thomas Lectka
Affiliations

Bifunctional asymmetric catalysis: a tandem nucleophile/Lewis acid promoted synthesis of beta-lactams

Stefan France et al. Org Lett. .

Abstract

[reaction: see text]. We describe a superior procedure for the catalytic, asymmetric synthesis of beta-lactams using a bifunctional catalyst system consisting of a chiral nucleophile and an achiral Lewis acid.

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