Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys
- PMID: 11980360
Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys
Abstract
The number of reports on in vivo gene therapies with decoy ODNs complexed with HVJ liposomes has recently increased. Diligent efforts to improve HVJ vectors as gene carriers and to expand the therapeutic applications of NFkB and E2F decoy ODNs will be important for the improved treatment of many genetic diseases.
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