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Case Reports
. 2002 May;40(5):1648-50.
doi: 10.1128/JCM.40.5.1648-1650.2002.

Disseminated toxoplasmosis, resulting from infection of allograft, after orthotopic liver transplantation: usefulness of quantitative PCR

Francoise Botterel  1 , P Ichai, C Feray, P Bouree, F Saliba, R Tur Raspa, D Samuel, S Romand
Affiliations
Case Reports

Disseminated toxoplasmosis, resulting from infection of allograft, after orthotopic liver transplantation: usefulness of quantitative PCR

Francoise Botterel et al. J Clin Microbiol. 2002 May.

Abstract

Disseminated toxoplasmosis is a life-threatening disease in liver transplant recipients that can result from an organ-transmitted infection. We report here a case of fatal disseminated toxoplasmosis after orthotopic liver transplantation from a seropositive donor (immunoglobulin G [IgG](+) and IgM(-)) in a patient who was nonimmune for toxoplasmosis prior to transplantation. Quantitative PCR analyses of various clinical specimens, including serum samples, appeared retrospectively to be a valuable diagnostic tool that might guide therapeutic attitudes.

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