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Comparative Study
. 2002 May;40(5):1818-20.
doi: 10.1128/JCM.40.5.1818-1820.2002.

Performance characteristics of VIDAS and directigen respiratory syncytial virus (RSV) antigen detection assays and culture for the identification of RSV in respiratory specimens

Julie A Ribes  1 , John Pat Seabolt, Sue B Overman
Affiliations
Comparative Study

Performance characteristics of VIDAS and directigen respiratory syncytial virus (RSV) antigen detection assays and culture for the identification of RSV in respiratory specimens

Julie A Ribes et al. J Clin Microbiol. 2002 May.

Abstract

In a comparison of the Directigen and VIDAS respiratory syncytial virus antigen detection assays with viral culture, the sensitivity, specificity, positive and negative predictive values, and testing efficiency were 86, 93.1, 82.7, 94.6, and 91.2% for Directigen; 96.1, 90.8, 80.3, 98.3, and 92.3% for VIDAS; and 88.2, 100, 100, 95.7, and 96.8% for viral culture, respectively.

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Figures

FIG. 1.
FIG. 1.
Number of days until culture detection of RSV in clinical specimens. The majority of specimens that were positive by culture were also positive by both Directigen and VIDAS (filled bars). Seven cultures were positive only by VIDAS (diagonal stripes), while one specimen was positive only by Directigen (horizontal stripes). A single culture was negative by both EIAs (open bar).
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