WNT signaling and lymphocyte development
- PMID: 11983149
- DOI: 10.1016/s0092-8674(02)00709-2
WNT signaling and lymphocyte development
Abstract
Developmental studies in model organisms have revealed that cell fate decisions are governed by only a handful of highly conserved signal transduction cascades. Recent data indicate that at least two of these, the Wnt and the Notch cascades, have been recruited by the vertebrate immune system to control early lymphopoiesis.
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