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Review
. 2002 Apr;9(4):700-2.
doi: 10.1016/s1097-2765(02)00512-9.

Sex and the single (double-strand) break

Emmanuelle Martini  1 , Scott Keeney
Affiliations
Free article
Review

Sex and the single (double-strand) break

Emmanuelle Martini et al. Mol Cell. 2002 Apr.
Free article

Abstract

It has been known for some time that DNA double-strand breaks (DSBs) initiate homologous recombination during meiosis. Two recent studies show that the fate of a single DSB in yeast is strongly influenced by the presence of other breaks in the genome, hinting that cell-wide or chromosome-regional mechanisms control the outcome of DSB repair.

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