An unusual two-tailed mouse

Abstract

A malformation that resulted in the formation of 2 complete tails is described in a mouse that was heterozygous for the sex-linked gene Bent-tail (Bn). One of the tails appeared normal and contained 29 vertebrae, whereas the other tail consisted of 27 vertebrae and had several bends or kinks in it and also had malformed vertebrae similar to those described for the Bn gene. A comparison of the malformation with previously described bifurcated tail conditions in the mouse is presented. It is possible that this 2-tailed mouse represents a special case of X-chromosome inactivation.