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Review
. 2002 May;95(5):227-30.
doi: 10.1177/014107680209500503.

The hypocretin/orexin system

Affiliations
Review

The hypocretin/orexin system

I O Ebrahim et al. J R Soc Med. 2002 May.
No abstract available

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Figures

<i>Figure 1</i>
Figure 1
Projections of the hypocretin (orexin) system (A), to cholinergic neurons, reticular formation and spinal cord; (B), to thalamus and basal ganglia; (C), to basal forebrain; (D), to amygdala and dopaminergic neurons including suprachiasmatic nucleus; (E), to locus coeruleus.

References

    1. Sutcliffe JG, de Lecea L. The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding. J Neurosci Res 2000;62: 161-8 - PubMed
    1. de Lecea L, Kilduff TS, Peyron C, et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 1998;95: 322-7 - PMC - PubMed
    1. Sakurai T, Amemiya A, Ishii M, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G-protein coupled receptors that regulate feeding behaviour. Cell 1998;92: 573-5 - PubMed
    1. Gautvik KM, de Lecea L, Gautvik VT, et al. Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction. Proc Natl Acad Sci USA 1996;93: 8733-8 - PMC - PubMed
    1. Peyron C. Distribution of immunoreactive neurons and fibers for a hypothalamic neuropeptide precursor related to secretin. Soc Neurosci Abstr 1997;23: 2032

MeSH terms