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Review
. 2002 Apr 30;121(1):1-10.
doi: 10.1016/s0166-6851(02)00028-2.

Development and applications of transgenesis in the yellow fever mosquito, Aedes aegypti

Zachary N Adelman  1 , Nijole Jasinskiene, Anthony A James
Affiliations
Free article
Review

Development and applications of transgenesis in the yellow fever mosquito, Aedes aegypti

Zachary N Adelman et al. Mol Biochem Parasitol. .
Free article

Abstract

Transgenesis technology has been developed for the yellow fever mosquito, Aedes aegypti. Successful integration of exogenous DNA into the germline of this mosquito has been achieved with the class II transposable elements, Hermes, mariner and piggyBac. A number of marker genes, including the cinnabar(+) gene of Drosophila melanogaster, and fluorescent protein genes, can be used to monitor the insertion of these elements. The availability of multiple elements and marker genes provides a powerful set of tools to investigate basic biological properties of this vector insect, as well as the materials for developing novel, genetics-based, control strategies for the transmission of disease.

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