And now, transcriptomics
- PMID: 11988161
- DOI: 10.1016/s0896-6273(02)00680-3
And now, transcriptomics
Abstract
In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims. The authors speculate on a possible serotonergic mechanism controlling 5-HT2C pre-mRNA editing.
Comment on
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Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims.Neuron. 2002 Apr 25;34(3):349-56. doi: 10.1016/s0896-6273(02)00660-8. Neuron. 2002. PMID: 11988167
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