Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase
- PMID: 11988746
- DOI: 10.1038/ncb0502-e110b
Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase
Comment on
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Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.Nat Cell Biol. 2000 Jul;2(7):428-34. doi: 10.1038/35017062. Nat Cell Biol. 2000. PMID: 10878808
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New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage.Nat Cell Biol. 2001 May;3(5):507-11. doi: 10.1038/35074581. Nat Cell Biol. 2001. PMID: 11331880
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