Chronic granulomatous disease mutations and the PX domain

Comment

Paul G Heyworth et al. Nat Cell Biol. 2002 May.

. 2002 May;4(5):E110.

doi: 10.1038/ncb0502-e110a.

No abstract available

Comment on

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.
Cheever ML, Sato TK, de Beer T, Kutateladze TG, Emr SD, Overduin M. Cheever ML, et al. Nat Cell Biol. 2001 Jul;3(7):613-8. doi: 10.1038/35083000. Nat Cell Biol. 2001. PMID: 11433291
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K.
Kanai F, Liu H, Field SJ, Akbary H, Matsuo T, Brown GE, Cantley LC, Yaffe MB. Kanai F, et al. Nat Cell Biol. 2001 Jul;3(7):675-8. doi: 10.1038/35083070. Nat Cell Biol. 2001. PMID: 11433300
PX domains: attracted by phosphoinositides.
Simonsen A, Stenmark H. Simonsen A, et al. Nat Cell Biol. 2001 Aug;3(8):E179-82. doi: 10.1038/35087112. Nat Cell Biol. 2001. PMID: 11483972 Review. No abstract available.