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Comparative Study
. 2002 May;43(5):635-9.

Multicenter comparison of calibration and cross calibration of PET scanners

Lilli Geworski  1 , Bernd O Knoop, Maike de Wit, Velimir Ivancević, Roland Bares, Dieter L Munz
Affiliations
  • PMID: 11994527
Free article
Comparative Study

Multicenter comparison of calibration and cross calibration of PET scanners

Lilli Geworski et al. J Nucl Med. 2002 May.
Free article

Abstract

The purpose of this study was to compare the calibration of PET scanners and their cross calibration to peripheral devices in a multicenter study.

Methods: Twenty-three dedicated PET scanners were investigated, applying standardized protocols. To ensure exact determination of the activity used, dose calibrators were checked using (68)Ge standards.

Results: Nine of 19 and 11 of 20 scanners displayed an error of <5% in 3-dimensional and 2-dimensional acquisition modes, respectively. Four and 5 scanners displayed an error of 10% in 3-dimensional and 2-dimensional modes, respectively. All other scanners yielded errors of 5% to <10%. Because of hardware and software problems, the measurements performed on 1 scanner could not be adequately analyzed.

Conclusion: An investigation of calibration is mandatory. Especially for quantitative analyses in clinical multicenter trials, identification of potentially miscalibrated scanners is necessary.

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