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Review
. 2002 Mar;3(3):195-205.
doi: 10.1038/nrm760.

Messenger-RNA-binding proteins and the messages they carry

Gideon Dreyfuss  1 , V Narry Kim, Naoyuki Kataoka
Affiliations
Review

Messenger-RNA-binding proteins and the messages they carry

Gideon Dreyfuss et al. Nat Rev Mol Cell Biol. 2002 Mar.

Abstract

From sites of transcription in the nucleus to the outreaches of the cytoplasm, messenger RNAs are associated with RNA-binding proteins. These proteins influence pre-mRNA processing as well as the transport, localization, translation and stability of mRNAs. Recent discoveries have shown that one group of these proteins marks exon exon junctions and has a role in mRNA export. These proteins communicate crucial information to the translation machinery for the surveillance of nonsense mutations and for mRNA localization and translation.

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