Palladium-catalyzed multiple arylation of thiophenes
- PMID: 11996567
- DOI: 10.1021/ja0259279
Palladium-catalyzed multiple arylation of thiophenes
Abstract
Secondary 2-thiophenecarboxamides efficiently undergo unique triarylation accompanied by formal decarbamoylation under palladium catalysis. 3-Substituted thiophenes, especially having an electron-withdrawing group, can also be triarylated.
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