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Review
. 2002 Jun;4(3):270-4.
doi: 10.1007/s11926-002-0076-z.

Pathogenesis of hyperuricemia: recent advances

Manisha Ghei  1 , Mihaela Mihailescu, Dennis Levinson
Affiliations
Review

Pathogenesis of hyperuricemia: recent advances

Manisha Ghei et al. Curr Rheumatol Rep. 2002 Jun.

Abstract

The literature on the pathogenesis of hyperuricemia have been limited to the discussion of metabolic syndromes associated with risk factors for atherosclerosis and hyperuricemia and the genetics of the juvenile form of hyperuricemic nephropathies. A few new mutations in the hypoxanthine-guanine phosphoribosyltransferase gene, which result in Lesch-Nyhan syndrome, have been described. In addition, some new insight has been gained in the renal handling of uric acid by the human kidney.

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References

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