The relationship of plasma to erythrocyte lithium levels in patients taking lithium carbonate
- PMID: 1201455
- DOI: 10.1192/bjp.127.6.596
The relationship of plasma to erythrocyte lithium levels in patients taking lithium carbonate
Abstract
Plasma and erythrocyte lithium levels have been determined repeatedly in twelve patients taking lithium carbonate for affective disorders. In any individual the plot of the plasma lithium level against erythrocyte/plasma ratio is linear, but the ratio can either increase or decrease with increasing plasma lithium concentration. Erythrocyte/plasma ratio is an unsound basis for comparing individual responses to lithium.
Similar articles
-
Letter: Intracellular lithium concentration and clinical response.Br J Psychiatry. 1975 Mar;126:298-300. doi: 10.1192/bjp.126.3.298-a. Br J Psychiatry. 1975. PMID: 1137652 No abstract available.
-
Lithium erythrocyte: plasma ratio in primary affective disorder.Compr Psychiatry. 1978 Mar-Apr;19(2):129-34. doi: 10.1016/0010-440x(78)90057-3. Compr Psychiatry. 1978. PMID: 630855 No abstract available.
-
Lithium erythrocyte/plasma ratio as a predictor of response.Am J Psychiatry. 1978 Mar;135(3):336-8. doi: 10.1176/ajp.135.3.336. Am J Psychiatry. 1978. PMID: 626224
-
[Blood cell lithium index in its pathogenic and clinical aspects].Psychiatr Pol. 1977 Jul-Aug;11(4):459-62. Psychiatr Pol. 1977. PMID: 339252 Review. Polish. No abstract available.
-
Lithium carbonate. A survey of the history and current status of Lithium in treating mood disorders.Dis Nerv Syst. 1971 Aug;32(8):521-31. Dis Nerv Syst. 1971. PMID: 4937542 Review. No abstract available.
Cited by
-
Intra and extra erythrocyte lithium ion concentration ratios in manic patients.Indian J Psychiatry. 1980 Apr;22(2):176-8. Indian J Psychiatry. 1980. PMID: 22064372 Free PMC article.
-
Serum level monitoring and clinical pharmacokinetics of lithium.Clin Pharmacokinet. 1977 Mar-Apr;2(2):73-92. doi: 10.2165/00003088-197702020-00001. Clin Pharmacokinet. 1977. PMID: 324690 Review.
-
Risk factors of thyroid abnormalities in bipolar patients receiving lithium: a case control study.BMC Psychiatry. 2003 May 10;3:4. doi: 10.1186/1471-244X-3-4. Epub 2003 May 10. BMC Psychiatry. 2003. PMID: 12740023 Free PMC article.
-
Population pharmacokinetic modeling of sustained release lithium in the serum, erythrocytes and urine of patients with bipolar disorder.Eur J Clin Pharmacol. 2019 Apr;75(4):519-528. doi: 10.1007/s00228-018-2605-3. Epub 2018 Dec 15. Eur J Clin Pharmacol. 2019. PMID: 30554270
-
Studies on the lithium transport across the red cell membrane. I.V. Interindividual variations in the Na+-dependent Li+ countertransport system of human erythrocytes.Pflugers Arch. 1977 Sep 16;370(3):211-9. doi: 10.1007/BF00585529. Pflugers Arch. 1977. PMID: 563051 No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources