Review
doi: 10.1016/s1534-5807(02)00182-x.
Cyclin G: a regulator of the p53-Mdm2 network
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- PMID: 12015958
- DOI: 10.1016/s1534-5807(02)00182-x
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Review
Cyclin G: a regulator of the p53-Mdm2 network
Dev Cell.
2002 May.
Free article
Abstract
A recent study published in the April issue of Molecular Cell has shown that cyclin G, a p53 target, is a regulatory component of the active PP2A holoenzyme, which activates Mdm2 through dephosphorylation. These findings suggest that cyclin G is a key regulator of the p53-Mdm2 network.
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