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. 1975 Dec;86 Suppl 2(3 Pt 2):593-8.
doi: 10.1002/jcp.1040860504.

Initiation of 3T3 fibroblast cell division by epidermal growth factor

S P Rose, R M Pruss, H R Herschman

Initiation of 3T3 fibroblast cell division by epidermal growth factor

S P Rose et al. J Cell Physiol. 1975 Dec.

Abstract

Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.

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