ATP-sensitive K(+) channels in the brain: sensors of hypoxic conditions
- PMID: 12021384
- DOI: 10.1152/nips.01384.2001
ATP-sensitive K(+) channels in the brain: sensors of hypoxic conditions
Abstract
Rapid minimization of energy consumption in excitable tissues is effective protection from lethal effects of extreme metabolic stress. The ATP-sensitive K(+) channels in the brain respond in ATP-depleted metabolic states such as hypoxia and may be involved in the protection mechanism against energy-consuming generalized seizure.