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. 2002 Jun;4(2):77-81.
doi: 10.1053/jfms.2001.0159.

Long-term outcome of eight cats with non-lymphoproliferative nasal tumours treated by megavoltage radiotherapy

R J Mellanby  1 , M E Herrtage, J M Dobson
Affiliations

Long-term outcome of eight cats with non-lymphoproliferative nasal tumours treated by megavoltage radiotherapy

R J Mellanby et al. J Feline Med Surg. 2002 Jun.

Abstract

A retrospective study was undertaken to evaluate the long term survival of eight cats with non-lymphoproliferative nasal tumours treated by megavoltage radiotherapy alone. Adenocarcinoma was the most commonly diagnosed tumour. Megavoltage radiotherapy was given to eight cats in 4-6 fractions of 4-8 Gys over a 16 to 28 day period. Seven cats completed the radiotherapy schedule and only two cases developed mild acute radiotherapy side effects. Median survival time after the completion of the radiotherapy course as calculated by Kaplan-Meier survival analysis was 382 days. The 1 year survival rate was 63%. All cats were euthanased because of either a poor response to radiotherapy or recurrence of the nasal tumour. This study demonstrates that a coarse fractionation regime of megavoltage radiotherapy can provide effective long-term palliative treatment for feline nasal tumours. The coarse fractionation schedule has the advantages of requiring only four to six treatments.

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Figures

Fig 1.
Fig 1.
Kaplan-Meier graph of survival from the start of radiotherapy treatment (n=8).
See this image and copyright information in PMC

References

    1. Adams WM, Withrow SJ, Walshaw R, Turrell JM, Evans SM, Walker MA, Kurzman ID. (1987) Radiotherapy of malignant nasal tumors in 67 dogs. Journal of American Veterinary Medical Association 191, 311–315. - PubMed
    1. Cox NR, Brawner WR, Powers RD, Wright JC. (1991) Tumors of the nose and paranasal sinuses in cats: 32 cases with comparison to a national database (1977 through 1987). Journal of American Animal Hospital Association 27, 339–347.
    1. Davidson AP, Mathews KG, Koblik PD, Theon A. (2000) Diseases of the nose and nasal sinuses. In Textbook of Veterinary Internal Medicine (5th edn). Ettinger SJ, Feldman EC. (eds). W.B. Saunders Company: Philadelphia, pp. 1003–1025.
    1. Evans SM, Hendrick M. (1989) Radiotherapy of feline nasal tumors: A retrospective study of nine cases. Veterinary Radiology 30, 128–132.
    1. Hahn KA, Knapp DW, Richardson RC, Matlock CL. (1992) Clinical response of nasal adenocarcinoma to cisplatin chemotherapy in 11 dogs. Journal of American Veterinary Medical Asssociation 200, 355–357. - PubMed

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