[Ribonucleases of rat liver nuclear membranes]
[Article in
Russian]
- PMID: 1203359
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[Ribonucleases of rat liver nuclear membranes]
[Article in
Russian]
Biokhimiia.
1975 Mar-Apr.
Abstract
A comparative study of ribonuclease activity of isolated rat liver nuclei, nuclear membranes with buoyant density rho 1,19 and rho 1,22 and pH 8 nuclear membrane extract showed high nuclear membranes activity with different affinity to RNA and synthetic polyribonucleotides. Chromatographic analysis of poly-U degradation products demonstrates that the nuclear membrane extract contains at least two ribonucleases: a 3'-endonuclease and a 5'-endonuclease.
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