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. 1975 Mar-Apr;40(2):384-8.

[Ribonucleases of rat liver nuclear membranes]

[Article in Russian]
A D Skridonenko
  • PMID: 1203359

[Ribonucleases of rat liver nuclear membranes]

[Article in Russian]
A D Skridonenko. Biokhimiia. 1975 Mar-Apr.

Abstract

A comparative study of ribonuclease activity of isolated rat liver nuclei, nuclear membranes with buoyant density rho 1,19 and rho 1,22 and pH 8 nuclear membrane extract showed high nuclear membranes activity with different affinity to RNA and synthetic polyribonucleotides. Chromatographic analysis of poly-U degradation products demonstrates that the nuclear membrane extract contains at least two ribonucleases: a 3'-endonuclease and a 5'-endonuclease.

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