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. 2002 Jul 15;365(Pt 2):343-7.
doi: 10.1042/BJ20020793.

Fate of haem iron in the malaria parasite Plasmodium falciparum

Timothy J Egan  1 , Jill M Combrinck, Joanne Egan, Giovanni R Hearne, Helder M Marques, Skhumbuzo Ntenteni, B Trevor Sewell, Peter J Smith, Dale Taylor, Donelly A van Schalkwyk, Jason C Walden
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Fate of haem iron in the malaria parasite Plasmodium falciparum

Timothy J Egan et al. Biochem J. .

Abstract

Chemical analysis has shown that Plasmodium falciparum trophozoites contain 61+/-2% of the iron within parasitized erythrocytes, of which 92+/-6% is located within the food vacuole. Of this, 88+/-9% is in the form of haemozoin. (57)Fe-Mössbauer spectroscopy shows that haemozoin is the only detectable iron species in trophozoites. Electron spectroscopic imaging confirms this conclusion.

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