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. 1975 Jan;19(1):143-7.

Activation of the classical and alternate pathways of complement by Corynebacterium parvum

W H McBride, D M Weir, A B Kay, D Pearce, J R Caldwell

Activation of the classical and alternate pathways of complement by Corynebacterium parvum

W H McBride et al. Clin Exp Immunol. 1975 Jan.

Abstract

The immunological adjuvant Corynebacterium parvum has been to activate the alternate pathway of complement in human and guinea-pig serum. Human serum in addition contains anti-C. parvum antibodies leading to activation of the classical complement pathway. The possible role of a C. parvum derived polysaccharide in this activation is considered in relation to the biological effects of the micro-organism.

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References

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